Amyloidosis
Amyloidosis is a group of rare but serious conditions caused by deposits of abnormal protein, called amyloid, in tissues and organs throughout the body.
AL amyloidosis can affect any organ, and the symptoms depend on which organs are affected. Most oftenamyloid is deposited in the kidneys and may cause kidney failure. Symptoms of kidney failure can i
AL amyloidosis occurs when an abnormality in the plasma cells found in bone marrow (the spongy tissue at the centre of some bones) results in the excessive production of proteins called 'light chains'
Diagnosis of AL amyloidosis can be challenging, since the symptoms are often very general. The diagnosis can be confirmed by removing a biopsy (small tissue sample) from the affected part of the bod
There are currently no treatments available that can directly remove the amyloid deposits associated with AL amyloidosis. Treatment aims to prevent the further production of abnormal light chains whil
Before effective treatments for AL amyloidosis were discovered, the outlook for the condition was poor, with many people only living for a few months. With modern treatments, the outlook varies depen
If you have amyloidosis, your clinical team will pass information about you on to the National Congenital Anomaly and Rare Diseases Registration Service (NCARDRS). This helps scientists look for bett